TIMP1 OVEREXPRESSION Detail (hg19) (TIMP1)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chrX:47,441,712-47,446,188 |
| hg38 | chrX:47,582,313-47,586,789 View the variant detail on this assembly version. |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| breast cancer | Fulvestrant | D |
Predictive
|
Supports
|
Resistance |
N/A
|
2 | 23881388 | Detail |
| breast cancer | Paclitaxel | B |
Predictive
|
Supports
|
Resistance |
N/A
|
2 | 22544540 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| TIMP1 overexpression was associated with resistance to fulvestrant in breast cancer cell lines. | CIViC Evidence | Detail |
| High expression of TIMP-1 was assessed by IHC in 99 primary breast cancers that had not spread beyon... | CIViC Evidence | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- TIMP1
- Genome
- hg19
- Position
- chrX:47,441,712-47,446,188
- Variant Type
- cnv
- Variant (CIViC) (CIViC Variant)
- OVEREXPRESSION
- Transcript 1 (CIViC Variant)
- ENST00000218388.4
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/377
Genome browser